GSC lines 

Click on the GCGR cell line ID to view the datasheet, which also has cell images, CNV data and STR profile
Click on the cell line profiling data columns for links to the data held at ENA and Array Express repositories

GCGR Cell line ID WHO classification Primary (P) or
recurrent tumour
GBM Transcriptional subclass Cell line profiling data Approx. cell doubling time
(hrs)
MGMT promoter methylation
methylated (M)/unmethylated (UnM)
Tumour formation
following transplant of GFP-Luc cell line
Classical/Proneural/Mesenchymal MesImm/NonMesImm Transcriptome Methylome Genome
GCGR-E1 glioblastoma, IDH wildtype P not assigned MESImm yes yes yes 120 UnM Yes (~8 months)
GCGR-E3 glioblastoma, IDH wildtype P classical Non-MESImm yes yes yes 84 M Yes (~10 months)
GCGR-E4 astrocytoma_high grade, IDH mutant P not GBM, astrocytoma_high grade, IDH mutant yes yes yes 336 M Not attempted
GCGR-E13 glioblastoma, IDH wildtype P classical MESImm yes yes yes 93.6 UnM Yes (~5 months)
GCGR-E15 glioblastoma, IDH wildtype P not assigned Non-MESImm yes yes yes 140 M Yes (~4 months)
GCGR-E17 glioblastoma, IDH wildtype P classical Non-MESImm yes yes yes 120 UnM Yes (~7 months)
GCGR-E20 glioblastoma, IDH wildtype P proneural equal yes yes yes 159 M Yes (~4 months)
GCGR-E21 glioblastoma, IDH wildtype P mesenchymal MESImm yes yes yes 232 UnM 40% mortality at 1 year
GCGR-E22 glioblastoma, IDH wildtype P classical Non-MESImm yes yes yes 151 UnM Yes (~10 months)
GCGR-E24 glioblastoma, IDH wildtype P proneural Non-MESImm yes yes yes 144 M Yes (~8 months)
GCGR-E25 glioblastoma, IDH wildtype P mesenchymal MESImm yes yes yes 202 UnM Yes (~8 months)
GCGR-E26 glioblastoma, IDH wildtype P classical Non-MESImm yes yes yes 168 UnM Yes (~9 months)
GCGR-E27 glioblastoma, IDH wildtype P not assigned MESImm yes yes yes 79 UnM No lethal brain tumours at 1 year (cells on top of brain ~8 months)
GCGR-E28 glioblastoma, IDH wildtype P classical Non-MESImm yes yes yes 101 M Yes (~6 months)
GCGR-E30 glioblastoma, IDH wildtype P classical Non-MESImm yes yes yes 154 UnM Yes (~11 months)
GCGR-E31 glioblastoma, IDH wildtype P proneural Non-MESImm yes yes yes 110 M Yes (~10 months)
GCGR-E34 glioblastoma, IDH wildtype P proneural Non-MESImm yes yes yes 144 UnM No lethal brain tumours at 1 year
GCGR-E35 glioblastoma, IDH wildtype P mesenchymal MESImm yes yes yes 73 UnM Yes (~9 months)
GCGR-E37 glioblastoma, IDH wildtype recurrent mesenchymal MESImm yes yes yes 84 UnM Yes (~4 months)
GCGR-E39 glioblastoma, IDH wildtype P mesenchymal MESImm yes yes yes 184 M No lethal brain tumours at 1 year
GCGR-E43 glioblastoma, IDH wildtype P classical Non-MESImm yes yes yes 140 M Yes (~3 months)
GCGR-E51 glioblastoma, IDH wildtype P mesenchymal MESImm yes yes yes 88 UnM Yes (~10 months)
GCGR-E53 glioblastoma, IDH wildtype P proneural Non-MESImm yes yes yes 108 UnM Yes (~7 months)
GCGR-E54 glioblastoma, IDH wildtype P proneural Non-MESImm yes yes yes 109 M 20% mortality at 5 months
GCGR-E55 glioblastoma, IDH wildtype P mesenchymal MESImm yes yes yes 65 UnM Yes (~4 months)
GCGR-E56 glioblastoma, IDH wildtype P classical Non-MESImm yes yes yes 73 M Yes (~5 months)
GCGR-E57 glioblastoma, IDH wildtype P mesenchymal MESImm yes yes yes 63 M Yes (~9 months)
GCGR-E58 astrocytoma_high grade, IDH mutant P not GBM, astrocytoma_high grade, IDH mutant yes yes 269 M Not attempted
GCGR-E62 glioblastoma, IDH wildtype recurrent not assigned equal yes yes yes 149 M Yes (~6 months)
GCGR-E63 glioblastoma, IDH wildtype P classical Non-MESImm yes yes yes 106 UnM Yes (~4 months)
GCGR-E64 glioblastoma, IDH wildtype P mesenchymal MESImm yes yes yes 132 M No lethal brain tumours at 1 year
GCGR-E65 glioblastoma, IDH wildtype P mesenchymal MESImm yes yes yes 134 UnM No lethal brain tumours at 1 year
GCGR-L1 glioblastoma, IDH wildtype P not assigned Non-MESImm yes yes yes 108 UnM Yes (~4 months)
GCGR-L2 glioblastoma, IDH wildtype P classical Non-MESImm yes yes yes 202 M Not attempted
GCGR-L3 glioblastoma, IDH wildtype P mesenchymal MESImm yes yes yes 186 UnM Yes (~3 months)
GCGR-L4 glioblastoma, IDH wildtype P mesenchymal MESImm yes yes yes 144 UnM Not attempted
GCGR-L5 glioblastoma, IDH wildtype recurrent classical Non-MESImm yes yes yes 128 UnM Yes (~4 months)
GCGR-L6 glioblastoma, IDH wildtype P proneural Non-MESImm yes yes yes 303 M Not attempted
GCGR-L7 glioblastoma, IDH wildtype P mesenchymal MESImm yes yes yes (no matching normal) 220 UnM Yes (~6 months)
GCGR-L8 astrocytoma_low grade, IDH mutant P not GBM, astrocytoma_high grade, IDH mutant yes yes yes 505 M No tumours at 1 year
GCGR-L10 glioblastoma, IDH wildtype P mesenchymal MESImm yes yes yes 77 UnM Yes (~8 months)
GCGR-L11 glioblastoma, IDH wildtype P not assigned equal yes yes yes (no matching normal) 237 UnM Yes (~9 months)
GCGR-L12 glioblastoma, IDH wildtype P mesenchymal MESImm yes yes yes 138 UnM No lethal brain tumours at 1 year
GCGR-L13 glioblastoma, IDH wildtype P mesenchymal equal yes yes yes 160 UnM No brain tumours at 1 year (cells on top of brain ~5month)
GCGR-L14 glioblastoma, IDH wildtype P not assigned MESImm yes yes yes 125 UnM Not attempted
GCGR-L15 glioblastoma, IDH wildtype P mesenchymal MESImm yes yes yes 160 M Yes (~10 months)
GCGR-L16 astrocytoma_high grade, IDH mutant P not GBM, astrocytoma_high grade, IDH mutant yes yes yes (no matching normal) 378 M Not attempted
GCGR-L17 glioblastoma, IDH wildtype P proneural Non-MESImm yes yes yes 134 M Not attempted
GCGR-L18 glioblastoma, IDH wildtype P not assigned equal yes yes yes 118 M No lethal brain tumours at 1 year
GCGR-L19 glioblastoma, IDH wildtype P classical Non-MESImm yes yes yes 147 UnM Not attempted
GCGR-L20 glioblastoma, IDH wildtype P mesenchymal MESImm yes yes yes 147 UnM No lethal brain tumours at 1 year
GCGR-L21 glioblastoma, IDH wildtype recurrent classical Non-MESImm yes yes yes 134 UnM Yes (~6 months)
GCGR-L22 glioblastoma, IDH wildtype P not assigned equal yes yes yes (no matching normal) 278 M Yes (~10 months)
GCGR-L23 glioblastoma, IDH wildtype P mesenchymal MESImm yes yes yes 285 UnM Not attempted
GCGR-L24 glioblastoma, IDH wildtype P not assigned MESImm yes yes yes 134 UnM Yes (~6 months)
GCGR-L25 glioblastoma, IDH wildtype P mesenchymal MESImm yes yes 160 UnM No lethal brain tumours at 1 year
GCGR-L26 glioblastoma, IDH wildtype P classical Non-MESImm yes yes yes 340 M Yes (~5 months)